Acute pre-renal failure: acquired chloride diarrhea after bowel resection

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Acute pre-renal failure: acquired chloride diarrhea after bowel resection

A 58-year old male with a history of small bowel resection and ileostomy presented with severe dehydration and high ostomy output. Laboratory investigation indicated hypochloremia, hypokalemia, hyponatremia, metabolic alkalosis, chloride-rich diarrhea, acute renal failure, and low urinary chloride excretion. Due to striking similarities to congenital chloridorrhea (CCD) reported in neonates, we...

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Renal abnormalities in congenital chloride diarrhea.

Congenital chloride diarrhea (CLD) is a rare autosomal recessive disorder caused by a defect in the chloride/ bicarbonate exchange in the ileum and colon. It is characterized by watery diarrhea, abdominal distension, hypochloremic hypokalemic metabolic alkalosis with high fecal content of chloride (>90 mmol/l). We report 3 patients with CLD associated with various renal abnormalities including ...

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ژورنال

عنوان ژورنال: Clinical Kidney Journal

سال: 2012

ISSN: 2048-8505,2048-8513

DOI: 10.1093/ckj/sfs082